In 2017, Chen et al. [24] performed a meta-analysis on the correlation between IGF1 and osteoporosis in a Chinese population and found that rs35767 in IGF1 was associated with risks of osteoporosis (OR = 1.31, 95% CI = 1.18–1.47, P value < 0.001), whereas other loci (e.g., rs2288377 and rs5742612) in IGF1 were not significantly correlated with osteoporosis. This evidence concerns the gene IGF1 and osteoporosis.