These relationships are supported by evidence which shows that many pathways and cell types implicated in cardiovascular disease (CVD) pathogenesis are regulated through vitamin D metabolites because most cardiovascular and inflammatory cells express vitamin D receptor (VDR) and CYP27B1, a mitochondrial 1α‐hydroxylase enzyme that catalyses the conversion of inactive vitamin D to its active form.10 Here, VDR is linked to cardiovascular disorder.