We have previously reported that the induction of Snail by TGF‐β is synergistically promoted by active Ras mutants such as H‐RasG12V and K‐RasG12D and that cancer cells harboring an active Ras mutation show dramatic induction of Snail following TGF‐β stimulation alone [15, 22]. The gene discussed is TGFB1; the disease is cancer.