INS and Hypoglycemia: Participants with fasting glucose <7 mmol/L spent 2.40% (IQR: 0.60–4.98) and 6.52% (IQR: 1.24– 13.50) of their total time per week in hypoglycemia, for SU and insulin, respectively, in comparison with only 0.0% (IQR: 0.00–0.46) and 0.67% (IQR: 0.00–3.44) for those who had fasting glucose ≥7 mmol/L (online supplemental table 1).