AURKA, a centrosome-associated serine/threonine kinase, has been shown to modulate essential mitotic events, including centrosome maturation, bipolar spindle assembly, and G2-M transition [28–30] and promote cell survival, migration, invasion, and proliferation in various cancer cells by activating AKT and FAK [17, 31, 32]. The gene discussed is AURKA; the disease is cancer.