Pathway analysis using changed SLC genes shows a dysregulated expression of SLC1A2, SLC7A8, SLC7A11, SLC9A1, SLC1A3, SLC18A2, SLC33A1, SLC4A7, SLC19A2 and SLC12A7 represented as a heatmap of four conditions to predict an increased tendency of neurodegenerative disease in KO cells (Figure 5D; Supplementary Table S3). This evidence concerns the gene SLC4A7 and neurodegenerative disease.