Children who consume a diet with a higher ratio of n-6:n-3 PUFA intake may be more susceptible to Crohn’s disease if they also carry SNPs in Cytochrome P450 Family 4 Subfamily F Member 3 (CYP4F3), Fatty Acid Desaturase 1 and 2 (FADS1, FADS2) (78). The gene discussed is FADS1; the disease is Crohn disease.