One patient developed DCM after 11 years of AF onset and he developed SCD soon after a decrease in ejection fraction within mild impairment (LVEF = 45%).Van Berlo et al. (32) demonstrated a 46% risk for SCD in a meta-analysis that includes 299 carriers of pathogenic LMNA gene variants; this risk was considered the same when the patients had a cardiac or neuromuscular phenotype or PM implantation. This evidence concerns the gene LMNA and atrial fibrillation.