CDKN2A and pancreatic adenocarcinoma: The CNV segments of the exocrine PDPCOs showed high concordance with the TCGA pancreatic adenocarcinoma (PAAD) dataset23, including the amplification of regions near KRAS, MYC and AKT2 and loss of regions near CDKN2A, TP53 and SMAD4 (Supplementary Fig. 2a).