Furthermore, the expression of NGF was detected by western blotting revealed that activating the HGF/c-Met signaling pathway promotes NGF expression in the pancreatic cancer cell lines PANC-1 cells (Fig. 2C and Supplementary Fig. S1C) and BxPC-3 cells (Fig. 2D and Supplementary Fig. S1F). Here, MET is linked to familial pancreatic carcinoma.