DAPK1 and gastric cancer: To elucidate whether M2 macrophage-derived EVs promote the metastasis of GC by regulating the expression of DAPK1, we first transfected plasmids of Vector and DAPK1 into GC cells, which were then co-incubated with the M2 macrophage-derived EVs (M2-EV + Vector and M2-EV + DAPK1).