In our MR analysis between levels of blood proteomes and stroke risk, we found 4 genes (MMP12, SCARF1, ABO, and F11), of which MMP12, ABO, and F11 were replicated, compared with a previous study that analyzed the association of circulating biomarker levels with stroke and stroke subtypes using a different study sample [46]. The gene discussed is SCARF1; the disease is stroke disorder.