The genes classifiers for ATLL_acute were enriched in Glutathione metabolism, Urea cycle and the metabolism of amino groups, beta-Alanine metabolism, Cysteine and methionine metabolism, sulfate activation for sulfonation, CXCR4-mediated signaling events, Metabolism of polyamines, Amino Acid metabolism, Metabolic pathways, Pathways in cancer, Hypoxia and p53 in the Cardiovascular system, Interferon Signaling, the planar cell polarity Wnt signaling, Noncanonical Wnt signaling pathway, Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. Here, CXCR4 is linked to cancer.