Twelve out of 26 writers including ADARB1, PABPN1, PCF11 and METTL3 were positively related to hazard ratio (HR) and significantly related to the cancer prognosis, and NUDT21, CLP1, RBM15B, CSTF2, WTAP, CPSF3, CPSF2 and RBM15 were negatively related to HR (Fig. 2A). The gene discussed is NUDT21; the disease is cancer.