In addition, GEPIA (Gene Expression Profiling Interactive Analysis) database (http://gepia.cancer-pku.cn/detail.php) was used to find out that expression of Lsm12 in many types of human malignant tumor tissues was also significantly upregulated compared with the paired normal tissues, which indicated that Lsm12 is a very critical gene in the tumorigenesis. Here, LSM12 is linked to cancer.