To investigate the expression of Lsm12 in the other malignant tumors, we used GEPIA database to find out that Lsm12 is also upregulated in many types of malignant tumors compared with the paired normal tissues, such as BRCA (Breast invasive carcinoma), CESC (Cervical squamous cell carcinoma and endocervical adenocarcinoma), CHOL (Cholangio carcinoma), COAD (Colon adenocarcinoma) (Fig. 3), which suggests that Lsm12 is closely associated with the tumorigenesis of human malignant tumors. The gene discussed is LSM12; the disease is colon adenocarcinoma.