PDE5A and diabetes mellitus: The ED risk factors and etiologies for the 54 men who responded insufficiently to PDE5-Is or prostaglandinE1 (PGE1) ICI and were treated with incobotulinumtoxinA IC 100U were as follows: cardio-metabolic including diabetes, spinal cord injury, post-radical prostatectomy or “no identified organic risk factor/etiology or other comorbidity” in respectively 25 (46%), 21 (39%), 14 (26%) and 6 (11%).