It activated the nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3 (NLRP3) inflammasome and nuclear factor-kappa B (NF-κB) signals, promoted leukocyte-EC adhesion, EC dysfunction, and vascular calcification and thus helped to enhance atherosclerosis processes [76,77,78,79]. This evidence concerns the gene NFKB1 and atherosclerosis.