That many dogs in our study were not considered to have AP despite both high DGGR-lipase activity and cPL concentrations is unsurprising given that several previous studies have shown elevations in both assays in association with nonpancreatic disorders in the absence of clinical pancreatitis [13,14,15,16,17,18,19,20,26,28]. This evidence concerns the gene HEPH and pancreatitis.