AUCs for a clinical diagnosis of AP, assigned to 87/301 dogs, with DGGR-lipase (0.75) and cPL (0.76) did not differ significantly (p = 0.48); optimal cutoffs were 161 U/L for DGGR (Se 67%; Sp 81%) and 235 μg/L for cPL (Se 68%; Sp 84%). This evidence concerns the gene HEPH and alkaline phosphatase measurement.