It is biologically plausible that the thyroid axis plays an important role in NAFLD development, as thyroid hormones (TH) are crucial in the regulation of numerous metabolic processes, such as cholesterol and lipid metabolism and intra-hepatic concentration, circulating lipoprotein levels, body weight, and insulin resistance [117,118,119,120]. The gene discussed is INS; the disease is metabolic dysfunction-associated steatotic liver disease.