Hence, ATB treatment was associated with an increased proportion of resident microglia (CD45low CD11b+ cells) and of glioma-associated microglia/macrophages (GAM, CD45high CD11b+ F4/80+) in the brain, specifically in GL261-bearing mice (Figure 3C) (p = 0.0173 and p = 0.0303, respectively). This evidence concerns the gene ITGAM and central nervous system cancer.