In accordance with our functional studies on permeability, no difference in the levels of mRNA encoding tight junctions proteins (Cldn1, Zo1, Ocln) and inflammatory cytokines (Il1b, Tnfa, Il6) was observed in the jejunum, ileum, or proximal colon between glioma-bearing and healthy mice (Figure S2). This evidence concerns the gene IL6 and central nervous system cancer.