Lung damage markers (namely, surfactant protein D—SP-D); cardiovascular disease markers (VCAM-1, ICAM-1, LDL, and TC); oxidative stress markers Superoxide Dismutase (SOD) and MDA; and inflammation markers (IL-8, IL-6, IL-1β, TNF-α, and IL-10) showed association with TiO2 nanoparticles’ concentration. The gene discussed is SFTPD; the disease is cardiovascular disorder.