TARDBP and Alzheimer disease: Hemispheric and subcortical regional specificity of targeted brain structures affected by air pollutant exposure is at the core of our interest in MMC highly exposed populations, knowing that in forensic samples with no extra-neural pathology, 99.5% of individuals 40 and younger have Alzheimer’s disease (AD) hallmarks, 23% have Parkinson’s disease (PD) and 18% TDP-43 pathology.