MAP2K1 and cancer: Furthermore, lncRNAs have been implicated in modulating various cancer-related signaling pathways, such as Wnt/β-catenin [9,10,11,12,13,14,15,16,17], PI3K/Akt/mTOR [18,19,20], Janus kinase/signal transducers and activators of transcription (JAK/STAT3) [21,22], mitogen-activated protein kinase 1 (MAPK) [23,24], nuclear factor-κB (NF-κB) [25,26], and NOTCH [27,28,29], and display the cancer phenotypes [9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29].