For example, DSP LP/P variants, p. S358L in the gene TMEM43 and PLN-pArg14, have been associated to a worse prognosis and elevated risk of SCD and a ring-like pattern of subepicardial left ventricle (LV) fibrosis can be identified and gives a high risk of SCD in FLNC and DES mutation carriers. Here, PLN is linked to Schnyder corneal dystrophy.