AKT1 and psychotic disorder: It is hypothesized that ameliorating maladaptive neuroplasticity in the cerebellum using NIBS will be crucial in CUD, since brain-wide AKT1 and FGFR1 gene expressions show hotspots in the cerebellum, as shown in Figure 4 (from https://neurosynth.org/ accessed on 30 December 2021), which makes it relevant for progression to psychotic disorder, especially with genetic predisposition [52].