IL17A and amebiasis: Figure 5E presented the top ten significantly enriched KEGG pathways of the DEGs (AD vs. PC100). The most significantly enriched pathway was the IL-17 signaling pathway. Others included pathways involved in cytokine-cytokine receptor interaction, such as Amoebiasis, Hematopoietic cell lineage and so on. To verify the KEGG enrichment results, we examined the mRNA expression level of Il-17a and Il-17f (members of the Il-17 family). The qPCR results indicated that PC significantly inhibited Il-17f expression.