Long non-coding RNA urothelial cancer-associated 1 (UCA1) has been reported as an upregulated oncogene factor in bladder cancer, positively modulating the formation of actin-dependent cell protrusions, proving to be essential in the dynamics of filopodia and therein in the promotion of migration and invasion of bladder cancer cell [93]. The gene discussed is UCA1; the disease is urinary bladder cancer.