FOXO1 and infection: In agreement with previous data, our strategy highlighted the following infection-driven processes: (1) macrophage immunosuppression as indicated by a M2 switch via CD163 and FoxO1 (blue boxes), (2) increased CD8 T cell infiltration (black boxes), (3) B and T cell proliferation via elevated Ki-67 correlation (yellow boxes), and (4) macrophage/FDC activation and function via increased CD169 and CD11b presence (green boxes) (Figure 5C).