PLEKHS1 and testicular germ cell tumor: Coinciding with the present findings Zhou et al. [22] by using the TCGA database, showed that PLEKHS1 was downregulated in stage I Testicular germ cell tumors (TGCTs) patients, and it was reported as one of the new eight-gene signatures that could be used in the prediction of relapse-free survival (RFS) having a protective role in TGCT relapse.