GSTM1 and acute kidney injury: The kidney is rarely affected by systemic Fe overload but can be specifically targeted, e.g. in the context of hemoglobin (Hb)-induced AKI subsequent to hemolysis, IRI or due to proteinuria associated with chronic kidney diseases (reviewed in Scindia Ph et al. 2019; Van Avondt et al. 2019; van Swelm et al. 2020).