VDR and neoplasm: In animal models, where tumour VDR signalling was apparently defective, vitamin D3 administration decreased survival and increased metastases, associated with downregulation of Th‐1 cells and INFG gamma and upregulation of MDSCs and TGFB (Anisiewicz et al., 2018; Cao et al., 2018) and upregulation of transcription of Tregs and Th‐2 cells (Pawlik et al., 2018).