NK cells lyse tumour cells via granzyme and TNFSF10 and FASLG, secrete cytokines, primarily Th‐1 type cytokines such as IFNG, TNF and granulocyte/ monocyte colony‐stimulating factor (CSF2) which facilitate the activation of T cells and other innate immune mediators (Walzer et al., 2005). This evidence concerns the gene TNF and neoplasm.