While SCD mutations have not been directly identified, there are numerous Parkinson’s risk factors that function in lipid metabolism or related functions, such as GBA, LRRK2, RAB7, VPS35, SYNJ1, ELOVL7, SCARB2, and SREBF-1, which is a transcription factor that regulates expression of lipogenic genes, including SCD [27, 28]. Here, GBA1 is linked to Parkinson disease.