Baseline immunological evaluation revealed neutropenia in 4/111 patients, lymphopenia in 20/112 patients, involving the CD3 + compartment in 22/92 patients, the CD4 + compartment in 15/92, the CD8 + compartment in 11/92, and the CD19 + compartment in 39/92. The gene discussed is CD8A; the disease is Decreased total neutrophil count.