The median plasma IgA and Gd-IgA1 concentrations among IgAN patients significantly were higher than those of the non-IgA nephropathy disease controls (DC) or healthy participant controls (HC) group (IgA:3.03 ± 0.86 g/L vs. 2.08 ± 0.75 vs. 1.89 ± 0.85; Gd-IgA1: 7.73 ± 3.98 μg/mL vs. 4.98 ± 3.36 vs. 5.51 ± 4.14, respectively). This evidence concerns the gene IGHA1 and IgA glomerulonephritis.