Several studies have reported that FABP5 plays a pivotal role in various diseases including metabolism disorders (e.g., obesity, insulin resistance, and T2DM) (Yeung et al., 2008), skin diseases (e.g., psoriasis) (Dallaglio et al., 2013), neurological diseases (e.g., Alzheimer’s disease) (Low et al., 2020), and carcinoma (e.g., prostate cancer, breast cancer, and cervical cancer) (Guaita-Esteruelas et al., 2018), due to its aberrant expression under pathological conditions. This evidence concerns the gene FABP5 and obesity disorder.