Recently, it has been reported that USP13 is co-overexpressed with c-Myc in many tumors, such as NSCLC (Wu et al., 2019), cholangiocarcinoma (CAA) (Zhou et al., 2020), GSCs (Fang et al., 2017), and hepatocellular carcinoma (HCC) (Huang et al., 2020). This evidence concerns the gene MYC and hepatocellular carcinoma.