Because the highly purified DND has complete adsorption of high levels of IL-8 normally released by A549 cells without cytotoxic effect (Supplementary Figures S1, S2), we hypothesized that DND could be a useful substance for clearing inflammatory mediators in the blood of CRS conditions such as COVID-19, sepsis, and pneumonia. This evidence concerns the gene CXCL8 and Sepsis.