Various cytokines including interleukins, interferon-gamma (IFN-γ), granulocyte-colony stimulating factor (G-CSF), intercellular adhesion molecule-1 (ICAM-1), matrix metalloproteinases (MMPs), C-reactive protein (CRP), and tumor necrosis factor-alpha (TNF-α) were increased in the plasma of COVID-19 patients compared to the normal group (Supplementary Figure S3). This evidence concerns the gene TNF and COVID-19.