Guo et al. showed, in a rat animal model, that antenatal LPS exposure was associated with increased levels of TNFA, aSMA, and extracellular matrix deposition in the glomeruli at 20 and 68 weeks of age, thereby confirming the association between chorioamnionitis and fibrotic changes in the glomeruli (17). The gene discussed is TNF; the disease is chorioamnionitis.