found that disease control rate (DCR) was 70% in TP53-mutated patients compared to 88% in TP53-wild type (TP53-wt) patients [relative risk, RR, of disease progression: 3.17 (95% CI 1.21-8.48), P=0.019] in 123 EGFR-mutated NSCLC patients receiving TKIs as first-line therapy (17). Here, EGFR is linked to non-small cell lung carcinoma.