These 11 genes were then individually studied the different roles that would play in the different histology of NSCLC, finding that none of them demonstrated a significant effect on OS in lung squamous cell carcinoma (LUSC; Table 3), while the other 9 genes, including ANLN, CCNA2, DEPDC1, DLGAP5, EXO1, KIAA0101, RRM2, TOP2A, and UBE2T, demonstrated potential in the prediction of survival based on the expression level in LUAD (Figures 3(l)–3(t)) rather than CDCA7 and HMMR (Table 3). The gene discussed is RRM2; the disease is squamous cell lung carcinoma.