IGHE and systemic lupus erythematosus: - Increased serum IL-25 protein levels in SLE patients - Serum IL-25 had positive correlation with disease severity and anti-dsDNA autoantibodies in SLE patients - Recombinant IL-25 suppressed inflammtory cytokine secretion from SLE PBMC cultures - Serum IL-25 cytokine had negative correlation with serum IL-5 and IgE levels in SLE patients