ALKBH5 also plays an oncogenic or tumor suppressive role in different kinds of cancers, such as breast cancer, glioblastoma, ovarian cancer, lung cancer, liver cancer, pancreatic cancer, gastrointestinal cancer, acute myeloid leukemia (AML) and osteosarcoma (14–20). This evidence concerns the gene ALKBH5 and familial pancreatic carcinoma.