GEPIA2 database analysis of the pan-cancer cohorts showed that OS was significantly reduced in BLCA (HR=1.5), LAML (HR=2.0), LGG (HR=1.6), and UVM (HR=4.9) patients with high ALKBH5 mRNA expression levels and significantly increased in CESC (HR=0.62) patients with high ALKBH5 mRNA expression levels (Figure 2F). The gene discussed is ALKBH5; the disease is cancer.