The gliomas are classified into the following three types according to the fifth edition of the World Health Organization (WHO) classification of tumors of the Central Nervous System (CNS) (WHO CNS5): IDH-mutant and 1p/19q-codeleted (mut+codel) oligodendroglioma, IDH-mutant (mut+non-codel) astrocytoma, and IDH-wildtype (IDH-wild) glioblastoma (42). Here, IDH1 is linked to neoplasm.