Genetic alterations such as the mutations, deletions, or amplifications of oncogenes or tumor suppressor genes are associated with growth and progression of several tumors (45). Therefore, we first analyzed different types of alterations including mutations, structural variations, amplifications, and deep deletions in the ALKBH5 gene in using the TCGA cancer datasets with the cBioPortal portal. The gene discussed is ALKBH5; the disease is cancer.