GSDME and hepatocellular carcinoma: Further analysis revealed that only 6 genes (CASP3, GSDME, NLRC4, NLRP6, NOD1, and PLCG1) are statistically correlated with the OS rate of HCC patients (p < 0.05) (Figure 4B and Supplementary Figure 4A), and only GSDME, NLRP6, and NOD1 are significantly correlated with the OS (p < 0.01).