SWI/SNF-related matrix-associated actin-dependent regulator of chromatin, family a, member 2 gene (SMARCA2), encoding the SWI/SNF subunit, Brahma (BRM), has been associated with self-reported MDD and SCZ (Amare et al., 2020; Wu et al., 2020a). This evidence concerns the gene SMARCA2 and major depressive disorder.