In a separate study, VAT but not SAT volume was associated with inflammatory markers [i.e., CRP, MCP-1, and intercellular adhesion molecule (ICAM)-1] in type 2 diabetics (117), and similarly, a correlation of white blood cell count and CRP with VAT but not SAT was found in a cohort of overweight individuals without diabetes, hypertension, or dyslipidemia (118). This evidence concerns the gene CRP and metabolic syndrome.