Figure 1 shows representative images of human arterioles treated with immunofluorescent antibodies against AdipoR1. AdipoR1 expression in arterioles from nonCAD patients is shown in Figure 1A and patients diagnosed with CAD in Figure 1B. Microvessels from individuals with and without CAD were treated intraluminally with siRNA against AdipoR1 Figure 1C. Cross-sections of the arterioles were immunolabeled for CD31 to outline the endothelium and allow for identification of endothelial AdipoR1. Figure 1D summarizes the immunofluorescent intensity in all 3 groups. This evidence concerns the gene PECAM1 and coronary artery disorder.