NFKB1 and gastric cancer: Finally, miR-362 and miR-505 overexpression were observed in gastric cancer cells (Xia et al., 2014; Wang Z. et al., 2020), and their enhanced expression promoted nuclear accumulation of NF-κB/p65, due to both miRs targeted CYLD directly and its downregulation mediated NF-κB activation.