In this way, high invasive potential, decreased E-cadherin expression and increased DDP-resistance has been founded in lung NCI-H1299, H596 and NCI-H522 cancer cells, due to a reduced miR-200c expression (Ceppi et al., 2010), and in liver Hep-G2 and Huh-7 cancer cells, also due to a decreased miR-31-5p expression (Chen et al., 2020). The gene discussed is CDH1; the disease is cancer.