Besides, FOXO3 also is regulated by miR-155 in colorectal cancer cells (Gao et al., 2018) and by miR-372 in gastric cancer cells (Wang C. et al., 2020), and enhanced FOXO3 expression by Akt promotes cell survival and resistance (Populo et al., 2012). This evidence concerns the gene FOXO3 and gastric cancer.