CCND1 and colorectal cancer: Cisplatin-resistant colorectal cancer cell lines, HCT 116/DDP and LoVo/DDP, have been shown to express low levels of miR-526-3p, compared with parental cells, and silencing of miR-526b-3p increases cyclin D1 expression and reduced cell cycle arrest, promoting thus DDP-resistance in colorectal cancer cells enhances (Zhang et al., 2021).