INSR and retinitis pigmentosa 1: To first characterize the possible role of INSR signaling in the dystrophic retina, we evaluated the retinal expression of each isoform in both physiological and pathological conditions: retinal Insr-a and Insr-b expression was analyzed by reverse transcriptase polymerase chain reaction (RT-PCR) in WT mice and in the Pde6brd10/rd10 (rd10) mouse model of RP [26].