Univariate analysis revealed the following as significantly associated with overall survival (OS, months): mALBI grade 2b or 3, tumor node metastasis (TNM) stage, alpha fetoprotein (AFP) ≥ 56.7 ng/dL, receiving other treatments after discontinuing LEN, and severe muscle atrophy (ΔPMI/m ≥ 1%) (Table 3). This evidence concerns the gene AFP and neoplasm.