Moreover, because VGLUT3 regulates specialized brain circuitries involved in reward processing, emotional states, and motor coordination, this neuronal adaption of GluR densities might provide a more comprehensive understanding of VGLUT3-dependent mechanisms underlying various neurologic and neuropsychiatric disorders such as anxiety (Amilhon et al., 2010), drug addiction (Sakae et al., 2015), or motor disorders such as Parkinson’s disease (Divito et al., 2015; Ribeiro et al., 2017). This evidence concerns the gene SLC17A8 and Parkinson disease.